منابع مشابه
Neural aspects of ghrelin-induced gastroprotection against mucosal injury induced by noxious agents.
Ghrelin, identified in oxyntic mucosa has been recently implicated in the control of food intake and growth hormone (GH) release but whether this hormone can influence the gastric secretion and gastric mucosal integrity have been little studied. We compared the effects of intraperitoneal (i.p.) and intracerebroventricular (i.c.v.) administration of ghrelin on gastric secretion in rats equipped ...
متن کاملRole of opioid receptors in bombesin-induced grooming.
Bombesin, a tetradecapeptide originally isolated from the skin of the frog Bombina bombina,’ elicits dose-related excessive grooming when injected centrally in rats2-‘ as well as other specie^.^ The grooming induced by intracerebroventricular (i.cv.) bombesin in rats consists of hindlimb scratching directed primarily at the head and neck, although facial grooming, body washing, nail licking and...
متن کاملCholecystokinin secretagogue-induced gastroprotection: role of nitric oxide and blood flow.
This study was done to examine the role of CCK in gastric mucosal defense and to assess the gastroprotective roles of nitric oxide and blood flow. In rats, the CCK secretagogues oleate and soybean trypsin inhibitor augmented gastric mucosal blood flow and prevented gastric injury from luminal irritants. Type A CCK receptor blockade negated CCK secretagogue-induced gastroprotection and exacerbat...
متن کاملPeptidergic and cholinergic neurons and mediators in peptone-induced gastroprotection: role of cyclooxygenase-2.
This study investigates the neural pathways, mediators, and cyclooxygenase isoenzymes involved in the gastroprotection conferred by peptone in rats. Intragastric perfusion with 8% peptone protected against gross and histological damage induced by subsequent perfusion with 50% ethanol. The gastroprotective effect of peptone was near maximally inhibited by gastrin immunoneutralization, inactivati...
متن کاملBrain-gut axis in gastroprotection by leptin and cholecystokinin against ischemia-reperfusion induced gastric lesions.
Leptin, a product of ob gene controlling food intake, has recently been detected in the stomach and shown to be released by CCK and implicated in gastroprotection against various noxious agents but it is unknown whether centrally applied leptin influences ischemia-reperfusion (I/R)-induced gastric erosions that progress into deeper gastric ulcerations. In this study we compared the effects of l...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Annals of Surgery
سال: 2005
ISSN: 0003-4932
DOI: 10.1097/01.sla.0000151790.14274.5d